Publications

Refereed Journal Articles published/in press/under review (click on journal title to link to paper):

  1. Madhumala K Sadanandappa, Shivaprasad H Sathyanarayana, Giovanni Bosco (2023). Parasitoid wasp culturing and assay to study parasitoid-induced reproductive modifications in Drosophila. Bio-Protocols Vol 13(0) Jan 5, 2023. doi: 10.21769.BioProtoc.4582

  2. Sebastian Zeltzer, Pierce Longmire, Marek Svoboda, Giovanni Bosco, Felicia Goodrum (2022). Host translesion polymerases are required for viral genome integrity. Proc Natl Acad Sci U S A 2022 Aug 16;119(33):e2203203119.

    doi: 10.1073/pnas.2203203119. Epub 2022 Aug 10.

  3. Shivaprasad H Sathyanarayana, Jasmine A Saunders, Jacob Slaughter, Kamran Tariq, Rajarshi Chakrabarti, Madhumala K Sadanandappa, Bryan W Luikart, Giovanni Bosco (2022). Pten heterozygosity restores neuronal morphology in fragile X syndrome mice. Proc Natl Acad Sci U S A 2022 Apr 12;119(15):e2109448119.

    doi: 10.1073/pnas.2109448119. Epub 2022 Apr 8.

  4. Marek Svaboda, H. Robert Frost, Giovanni Bosco (2022). Internal oligo(dT) priming in bulk and single cell RNA sequencing. NAR Genom Bioinform. 2022 May 25;4(2):lqac035. doi: 10.1093/nargab/lqac035. eCollection 2022

  5. Marek Svaboda, H. Robert Frost, Giovanni Bosco (2021). Internal oligo(dT) priming in bulk and single cell RNA sequencing. BioRxiv doi: https://doi.org/10.1101/2021.09.24.461289.

  6. Madhumala K. Sadanandappa, Shivaprasad H. Sathyanarayana, Shu Kondo, Giovanni Bosco (2021). Neuropeptide F signaling regulates parisitoid-specific germline development and egg-laying in Drosophila. PLoS Genetics 17(3):e1009456. https://doi.org/10.1371/journal.pgen.1009456

  7. Emily Weyburne and Giovanni Bosco (2020). Cancer-associated mutations in the condensin II subunit CAPH2 cause genomic instability through telomere dysfunction and anaphase chromosome bridges. J Cell Physiol. 2020 Oct 20.

     doi: 10.1002/jcp.30113.

  8. Katie A. Edwards, Michael B. Hoppa and Giovanni Bosco (2020). The photoconvertible fluorescent probe, CaMPARI, labels active neurons in freely-moving intact adult fruit flies. Front Neural Circuits. 2020 May 8;14:22.

    doi: 10.3389/fncir.2020.00022. eCollection 2020.

  9. Heather Wallace, Vibhuti Rana, Huy Nguyen and Giovanni Bosco (2019). Condensin II subunit NCAPH2 associates with shelterin protein TRF1 and is required for telomere stability. J Cell Physiol. 2019 Nov;234(11):20755-20768. doi: 10.1002/jcp.28681. Epub 2019 Apr 26.

  10. Balint Kacsoh, Julianna Bozler, Sassan Hodge and Giovanni Bosco (2019). Neural circuitry of social learning in Drosophila requires multiple inputs to facilitate inter-species communication. Commun Biol. 2019 Aug 13;2:309. doi: 10.1038/s42003-019-0557-5. eCollection 2019.

  11. Julianna Bozler, Balint Kacsoh and Giovanni Bosco (2019). Transgenerational inheritance of ethanol preference is caused by maternal NPF repression. Elife. 2019 Jul 9;8. pii: e45391. doi: 10.7554/eLife.45391.

  12. MJ Rowley, X Lyu X, V Rana, M Ando-Kuri, R Karns, G Bosco, VG Corces.(2019). Condensin II Counteracts Cohesin and RNA Polymerase II in the Establishment of 3D Chromatin Organization. Cell Rep. 2019 Mar 12;26(11):2890-2903.e3. doi: 10.1016/j.celrep.2019.01.116.

  13. Balint Kacsoh, Stephen Barton, et al. (2019). New Drosophila long-term memory genes revealed by assessing computational function prediction methods. G3 (Bethesda). 2019 Jan 9;9(1):251-267. doi: 10.1534/g3.118.200867.

  14. Balint Kacsoh, Julianna Bozler and Giovanni Bosco (2018). Drosophila species learn dialects through communal living. PLoS Genet 14(7): e1007430. https://doi.org/10.1371/journal.pgen.1007430.

  15. Julianna Bozler, Balint Kacsoh, Hao Chen, William E. Theurkauf, Zhiping Weng and Giovanni Bosco (2017). A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes. PLoS Genet 13(10): e1007054. https://doi.org/10.1371/journal.pgen.1007054

  16. Balint Kacsoh, Casey Greene and Giovanni Bosco. (2017). Machine Learning Analysis Identifies Drosophila Grunge/Atrophin as an Important Learning and Memory Gene Required for Memory Retention and Social Learning. G3 (Bethesda). 2017 Sep 9. pii: g3.300172.2017. doi: 10.1534/g3.117.300172. (PMID: 28889104)

  17. Balint Kacsoh, Julianna Bozler, Mani Ramaswami and Giovanni Bosco. (2015). Social communication of predator-induced changes in Drosophila behavior and germline physiology. eLife 2015 May 13;4 doi:10.7554/eLife.07423. (PMID:25970035). Click here to see F1000 recommendation.

  18. Balint Kacsoh, Julianna Bozler, Sassan Hodge, Mani Ramaswami and Giovanni Bosco. (2015). A Novel Paradigm for Nonassociative Long-Term Memory in Drosophila: Predator-Induced Changes in Oviposition Behavior. GENETICS. 2015 Apr;199(4):1143-57. doi:10.1534/genetics.114.17222. Epub 2015 Jan 29. (PMID: 25633088).

  19. Li Li, Xiaowen Lyu, Chunhui Hou, Naomi Takenaka, Huy Q. Nguyen, Chintong Ong, Caelin Cubeñas-Potts, Ming Hu, Elissa P. Lei, Giovanni Bosco, Zhaohui S. Qin and Victor G. Corces. (2015). Widespread rearrangement of 3D chromatin organization underlies Polycomb-mediated stress-induced silencing. Molecular Cell. 2015 Apr 16;58(2):216-31. doi: 10.1016/j.molcel.2015.02.023. Epub 2015 Mar 26. (PMID:25818644)

  20. Heather A. Wallace, Joseph E. Klebba, Thomas Kusch, Gregory C. Rogers and Giovanni Bosco. (2015) Condensin II regulates interphase chromatin organization through the Mrg binding motif of Cap-H2. G3 G3 (Bethesda). 2015 Mar 9;5(5):803-17. doi: 10.1534/g3.115.016634. (PMID:25758823)

  21. Huy Q Nguyen, Jonathan Nye, Daniel Buster, Joseph Klebba, Gregory C Rogers and Giovanni Bosco. (2015). Drosophila Casein Kinase 1 Alpha Regulates Homolog Pairing and Genome Organization by Modulating Condensin II Subunit Cap-H2 Levels. PLoS Genetics 11(2):e1005014. doi:10.1371 (PMID: 25723539)

  22. Julianna Bozler, Huy Q Nguyen, Gregory Rogers and Giovanni Bosco (2014). Condensins exert force on chromatin-nuclear envelope tethers to mediate nucleoplasmic reticulum formation in Drosophila melanogaster. G3 2014 Dec. 30. pii: g3.114.015685. doi: 10.1534/g3.114.015685. (PMID:25552604)

  23. Carolyn George, Julliana Bozler, Huy Q. Nguyen, and Giovanni Bosco (2014). Condensins are required for maintenance of nuclear architecture. CELLS 3(3):865-882(PMID: 25153163)

  24. Heather Wallace, JA Merkle, MC Yu, TG Berg, E Lee, G Bosco and LA Lee (2014). TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η.Development 2014 March;141(6):1332-41. (PMID 24553286)

  25. Helen F Smith, Meredith A Roberts, Huy Q Nguyen, Maureen Peterson, Tom A Hartl, Xiao-Jun Wang, Joseph E Klebba, Gregory C Rogers, Giovanni Bosco. (2013). Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin Cap-H2 and its partner Mrg15. GENETICS 2013 Sept.;195(1):127-46 (PMID: 23821596)

  26. Maureen Peterson, Vicki L. Chandler and Giovanni Bosco. (2013). High SINE RNA Expression Correlates with Post-transcriptional Downregulation of BRCA1. Genes 2013,4(2), 226-243; doi:10.3390/genes4020226

  27. Daniel W. Buster, Scott G. Daniel, Huy Q. Nguyen, Sarah L. Windler, Lara C. Skwarek, Maureen Peterson, Meredith Roberts, Joy H. Meserve, Tom Hartl, Joseph E. Klebba, David Bilder, Giovanni Bosco and Gregory C. Rogers (2013). SCF-Slimb ubiquitin-ligase suppresses condensin II-mediated nuclear reorganization by degrading Cap-H2. Journal of Cell Biology, 2013 Apr 1;201(1):49-63. doi: 10.1083/jcb.201207183. (PMID: 23530065)

  28. Christopher Bauer, Tom A Hartl and Giovanni Bosco (2012). Condensin II Promotes the Formation of Chromosome Territories by Inducing Axial Compaction of Polyploid Interphase Chromosomes. PLoS Genet 8(8): e1002873. doi:10.1371/journal.pgen.1002873 (PMID: 22956908)

  29. Sundaresh Ram, Jeffrey J. Rodriguez, and Giovanni Bosco (2012).Segmentation and Classification of 3-D Spots in FISH Images. Cytometry Part A 81A: 198-212. (PMID:22354758)

  30. Sundaresh Ram, Jeffrey J. Rodriguez, and Giovanni Bosco (2010). Segmentation and Classification of 3-D Spots in FISH Images. 2010 IEEE Southwest Symp. on Image Analysis and Interpretation, Austin, TX.

  31. Joseph Ahlander and Giovanni Bosco. (2009). Sqd interacts with the Drosophila retinoblastoma tumor suppressor Rbf. Biochem Biophys Res Commun. 2009 Jun 5;383(3):363-7. Epub 2009 Apr 11. (PMID: 19364495).

  32. Andrew M. Epstein, Christopher R. Bauer, Aaron Ho, Giovanni Bosco and Daniela C. Zarnescu. (2009). Drosophila Fragile X protein controls cellular proliferation by regulating cbl levels in the ovary. Dev Biol. Jun 1;330(1):83-92. Epub 2009 Mar 21. PMID: 19306863.

  33. Tom A. Hartl, Helen F. Smith and Giovanni Bosco. (2008). Chromosome alignment and transvection are antagonized by condensin II. Science. 2008 Nov 28;322(5906):1384-7. (PMID: 19039137).

  34. Christopher R. Bauer, Andrew M. Epstein, Sarah J. Sweeney, Daniela C. Zarnescu and Giovanni Bosco. (2008). Genetic and systems level analysis of Drosophilasticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks. BMC Syst Biol. 2008 Nov 25;2:101. (PMID: 19032789).

  35. Tom A. Hartl, Sarah J. Sweeney, Peter J. Knepler and Giovanni Bosco. (2008). Cap-H2 resolves chromosomal associations to enable anaphase I segregation inDrosophila male meiosis. PLoS Genet. 2008 Oct;4(10):e1000228. (PMID: 18927632).

  36. Joseph Ahlander, Xiao-Bo Chen, Paula Campbell and Giovanni Bosco. (2008). The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent manner. PLoS ONE. 2008 Jul 30;3(7):e2831. (PMID: 18665226).

  37. Sarah Sweeney, Paula Campbell and Giovanni Bosco. (2008). Drosophila sticky/citron kinase is a regulator of cell cycle progression and epigenetic gene silencing. Genetics. Mar;178(3):1311-25. (PMID: 18245345).

  38. Celine Hayden and Giovanni Bosco. (2008). Comparative genomic analysis of novel conserved peptide upstream open reading frames and associated major open reading frames in Drosophila melanogaster reveals an overrepresentation of mitochondria-targeted proteins, BMC Genomics. Feb 1;9:61. (PMID: 18237443).

  39. Wan-Pyo Hong, Wenqing Qi, Marc Brabant, Giovanni Bosco and Jesse D. Martinez. (2008). Human 14-3-3 gamma protein stimulates abnormal cell proliferation and interferes with differentiation in the developing eye of Drosophila melanogaster. Cell Div. Jan 14;3:2. (PMID: 18194556).

  40. Giovanni Bosco, Paula Campbell, Joao T. Leiva-Neto and Therese A. Markow (2007). Analysis of Drosophila species genome size and satellite DNA content reveals significant differences among strains as well as between species. Genetics. Nov;177(3):1277-90.(PMID: 18039867).

  41. Tom Hartl, Carl Boswell, Terry Orr-Weaver and Giovanni Bosco. (2007). Developmentally regulated histone modifications in Drosophila follicle cells: initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation. Chromosoma 116:197-214. (PMID: 17219175)

  42. Julie M. Claycomb, Matt Benasutti, Giovanni Bosco, Douglas D. Fenger and Terry Orr-Weaver. (2004). Gene amplification as a developmental strategy: Isolation of two developmental amplicons in Drosophila. Dev Cell. Jan;6(1):145-55. (PMID:14723854)

  43. Irena Royzman, Aki Hayashi-Hagihara, Kimberley J. Dej, Giovanni Bosco, Janice Y. Lee, and Terry L. Orr-Weaver. (2002). The E2F cell cycle regulator is required for Drosophila nurse cell DNA replication and apoptosis. Mechanisms of Development 119:225-237 (PMID: 12464435).

  44. Giovanni Bosco, Wei Du and Terry L. Orr-Weaver. (2001). DNA replication control through interaction of E2F-RB and the Origin Recognition Complex. Nature Cell Biol.3:289-295 (PMID: 11231579).

  45. Laurie A. Lee, Lisa K. Elfring, Giovanni Bosco and Terry L. Orr-Weaver. (2001) A genetic screen for suppressors and enhancers of the PAN GU cell cycle kinase identifies Cyclin B as a critical target. Genetics 158:1545-1556 (PMID: 11514446).

  46. Irena Royzman, Richard J. Austin, Giovanni Bosco, Stephen P. Bell and Terry L. Orr-Weaver. (1999) ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes and Dev. 13:827-840 (PMID: 10197983).

  47. Giovanni Bosco and James E. Haber. (1998) Chromosome break induced DNA replication leads to non-reciprocal translocationsand telomere capture. Genetics 150:1037-1047 (PMID: 9799256).

  48. Constance I. Nugent, Giovanni Bosco, Lyle O. Ross, Sara K. Evans, Andrew P. Salinger, J. Kent Moore, James E. Haber and Victoria Lundblad. (1998) Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr. Biol. 8:657-660 (PMID: 9635193).

  49. John H. Wilson, Wai-Ying Leung, Giovanni Bosco, De Dieu, and James E. Haber. (1994). The frequency of gene targeting in yeast depends on the number of target copies. Proc. Natl. Acad. Sci. 91:177-181 (PMID: 8278360).

 

Reviews and invited articles:

  1. Vibhuti Rana and Giovanni Bosco (2017). Condensin regulation of genome architecture. J. Cell. Physiol. 232: 1617–1625, 2017 . (PMID: 27888504)

  2. Heather A. Wallace and Giovanni Bosco (2013). Condensins and 3D Organization of the Interphase Nucleus. Current Genetic and Medicine Reports, September 27, 2013. e-ISSN 2167-4876.

  3. Giovanni Bosco (2012). Chromosome pairing: a hidden treasure no more. PLoS Genet. 2012;8(5):e1002737. doi: 10.1371/journal.pgen.1002737. (PMID: 22654678)

  4. Giovanni Bosco (2010). Cell Cycle: Retinoblastoma, a trip organizer. Nature. Aug 26;466(7310):1051-2

  5. Joseph Ahlander and Giovanni Bosco. (2009). The RB/E2F pathway and regulation of RNA processing. Biochem Biophys Res Commun. Jul 3;384(3):280-3. Epub 2009 May 3. Review. (PMID: 19401190)

  6. Giovanni Bosco (2009). When Segregation Hangs by a Thread. PLoS Genet. Feb;5(2):e1000371. (PMID: 19197362)

  7. Giovanni Bosco and Terry L. Orr-Weaver. (2002). Regulation of the cell cycle during oogenesis and early embryogenesis in Drosophila (pp.107-154), in Regulation of gene expression at the beginning of animal development. Editor: M. DePamphilis. Elsevier Publishing. Amsterdam

  8. David W. Deamer, Elizabeth Harang Mahon, and Giovanni Bosco (1992). Self-assembly and function of primitive membrane structures (pp.107-123), in Early Life on Earth. Editor: Stefan Bengtson, Jan Bergström, Gonzalo Vidal, Andrew Knoll: Columbia University Press, New York, USA